How There Was Never Any Evidence, Depression is Due to Chemical Imbalance in The Brain

ByPrimary Researcher

Table of Contents: Select a Link to be Taken to That Section

Executive Summary

  • SSRIs are based on the hypothesis that depression is due to a chemical imbalance in the brain.
  • This hypothesis has been disproven.

Introduction

The medical establishment has made enormous sums from SSRIs, the dominant category of antidepressants. Research published in the journal Nature now shows that the hypothesis of how SSRIs work cannot reduce depression. It is interesting to learn that the chemical imbalance in the brain hypothesis, as with the serotonin hypothesis, was put forward by pharmaceutical companies and was not established science.

Go to top

Stanford University on SSRIs

This research addresses something which is foundational to the claims of the effectiveness of SSRI or Selective Serotonin Reuptake Inhibitors based on antidepressants. The following video, delivered in a strange hushed tone from Stanford University, explains how SSRIs are hypothesized to work.

The reason Dr. Battista states that the “exact way SSRIs work is not known” is because the mechanism of SSRIs — which results in higher serotonin levels takes at least a month to occur; however, taking SSRIs can lead to an improvement in mood within hours. This does not match when serotonin levels begin to increase. This is a textbook placebo effect. Instead of admitting the placebo effect, pharma companies and the medical establishment stated that while the hypothesized mechanism is not how SSRIs work, they must “work in some other way.”

The reader should know that what I have written above was known for years before SSRIs were finally exposed in the Nature paper that I will soon provide excerpts. Therefore, the medical establishment knew that what Dr. Battista is describing in this video is not the mechanism. If the medical establishment followed a scientific approach, no SSRIs would have ever been approved. That is, SSRI results were never different from a placebo, and multiple copycat SSRIs were approved by the FDA anyway.= =At the 1:15 mark in the video, Dr. Battista switches from SSRIs to a general discussion of how serotonin regulates the brain — these things are true, but they have nothing to do with SSRIs or whether SSRIs work or not. All Dr. Battista is describing is what is known about SSRIs, but he is leaving out that medicine does not understand how to control serotonin. Dr. Battista is riding the line of deception here because he is deliberately commingling what is known about serotonin — without explaining that no SSRI ever invented addresses depression, even though it increases serotonin. Dr. Battista then goes on to provide the chemical imbalance in brain hypothesis (which, as I will show later, has been entirely disproven) — and what Dr. Battista does not do is cover external events that can lead to depression. This is consistent with medical practice on depression, where external negative events are treated as almost inconsequential. Addressing depression is not becoming more healthy or addressing negative events — it is taking SSRIs.