The Testing Evidence for Using Ivermectin for Treating Hairy Cell Leukemia Cancer

Executive Summary

• This article covers the evidence I could find for Ivermectin as a treatment for hairy cell leukemia cancer.

Article Summary

Studies demonstrate that Ivermectin is effective against cancer, we then cover how Ivermectin works against cancer by explaining the mechanisms of action, and then the impacts of Ivermectin on cancer.

Introduction

This article provides an overview covering the evidence for Ivermectin versus hairy cell leukemia cancer.

In many articles on this site, such as the article How Ivermectin Is Useful for Treating Cancer we covered the evidence for the benefits of Ivermectin for cancer. However, the topic of which specific cancers Ivermectin has been proven effective is a constant source of questions.

There are a lot of quotes in this article, but I have a short one for each cancer type. The article uses the term “IVM” to mean Ivermectin.

What is the Interest Level in the Search Topic Ivermectin Hairy Cell Leukemia Cancer?

The search for Ivermectin Hairy Cell Leukemia Cancer is a commonly searched cancer type concerning Ivermectin. After reviewing the available articles on the Internet, we found there is very little coverage of the effectiveness of Ivermectin for many specific types of cancer. In response, we created articles covering the effectiveness of Ivermectin for nearly all different cancers, including Ivermectin Hairy Cell Leukemia Cancer. You can see our full list of articles on the topic of Ivermectin versus the different cancers at The Cancers For Which Ivermectin Has Been Demonstrated to be Effective.

About the Brightwork Research Treatment Database

We have a subscription website that provides people with everything they need to know about using Ivermectin for several diseases. Cancer is just one of our most researched areas. To see more see the below article indexes. 

Article Indexes

• Open this link to see just one example Ivermectin article index.
• Open this link to see the full article index. 

We have the most research on Ivermectin and Ivermectin for cancer and are completely independent. However, we have to charge subscribers to stay independent. We have free articles that expose readers to our research and writing -- however most of our content is behind a paywall. 

Cancer Type #5: Hairy Cell Leukemia Cancer

Hairy cell leukemia cancer does not have Ivermectin studies yet published. However, given the performance of Ivermectin versus other types of cancer, it is very likely that Ivermectin is effective against hairy cell leukemia cancer.

The Mechanisms by Which Ivermectin Works Against Cancer

Confidence in Ivermectin being effective for many cancer types also comes from understanding the specific mechanisms by which Ivermectin works against cancer. I cover this topic in detail in the article By How Many Different Mechanisms Does Ivermectin Fight Cancer?

Impacts of Ivermectin on Cancer

The following are how Ivermectin works against cancer.

Impact #1: Inhibiting Proliferation of Tumor Cells

Recently, ivermectin has been reported to inhibit the proliferation of several tumor cells by regulating multiple signaling pathways.

The Ivermectin blocking of PAK1 proteins, aka activated kinase, is a reason for this.

The instrumentality of PAK1 in cancer growth is explained in the following quotation from the article Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations.

Impact #2: Inhibiting Metastasis

Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells.

Metastasis is how cancer spreads, and I cover this in detail in the article How Does Metastasis Work in the Body?

Impact #3: Promoting Apoptosis & Pyropoptsis

ivermectin promotes programmed cancer cell death, including apoptosis, autophagy, and pyropoptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Second, IVM seems to induce mixed cell death in tumor cells, which is also a controversial issue

A significant issue with the dysfunction of cancer is that the cancerous cells refuse instructions from the immune system to commit suicide -- or what is scientifically referred to as apoptosis. I cover apoptosis in the article How Ivermectin Improves Cancer Prevention and Treatment Through Improving Apoptosis or Programmed Cell Death.

Pyropoptosis is a type of apoptosis that is caused by inflammation.

Impact #4: Promoting Autophagy

Deng found that IVM could activate the nuclear translocation of TFE3 and induce autophagy-dependent cell death by dephosphorylation of TFE3 (Ser321) in SK-MEL-28 melanoma cells.

Autophagy clears away cells and recycles them. Different things can trigger more autophagy. I cover autophagy in the article Is Autophagy Effective Against Cancer?

Impact #5: Inhibit Cancer Cell Proliferation Through Inhibiting YAP1 Activity

Lung cancer has the highest morbidity and mortality among cancers. Nishio found that IVM could significantly inhibit the proliferation of H1299 lung cancer cells by inhibiting YAP1 activity.

Conclusion

There is ample evidence that Ivermectin is helpful against many different types of cancers. It is unlikely that these are the only cancers for which Ivermectin is effective, but the studies we have found so far show that Ivermectin works to combat and prevent it. Ivermectin is an immuno-modulator, so it has beneficial effects not only for cancer -- as one of the mechanisms of how Ivermectin works is improving the immune system, which means it improves the immune system against cancer and other diseases.

Regarding the dosage and sourcing of Ivermectin, see the article On the Topic of Ivermectin Dosage and Sourcing.

Why Are Anti-Parasitic Drugs Effective Against Cancer?

To understand why this class of drugs works against cancer, see the article The Mechanism of How Anti-Parasitic Drugs Work to Mitigate Cancer.

About Our Ivermecting Testing Program and Recommended Ivermectin Source of Supply

• We performed pharmaceutical testing on Ivermectin to find a lower-cost version that also matched Merck's original Ivermectin in bioequivalence.
• You can read about the details of our Ivermectin testing in this article, Our Ivermectin Bioequivalence Testing.
• We got Summit Products to carry this version of Ivermectin, which passed our bioequivalence testing.